PROCESS FOR THE SYNTHESIS OF N-SUBSTITUTED ß-AMINO NITRILES THROUGH THE RING OPENING OF AZIRIDINES

摘要

The present invention comprises the simultaneous ring opening and concomitant N-substitution of various W-tosyl aziridines with different aliphatic and aromatic nitriles in presence of catalytic amount of metal triflates to afford different yV-substituted ß-amino nitriles in excellent yields and selectivities.