AN IMPROVED PROCESS FOR THE PREPARATION OF ERYTHRONCYIN A (I) AND ERYTHROMYCIN A OXIME (II)

摘要

The present invention relates to the process for the preparation of Erythromycin A (I) substantially free of Erythromycin B (III) by treating Erythromycin thiocyanate with ammonia in halogenated solvent. Also Erythromycin A oxime (II) is prepared.