1. 2-Amino carbonyl-9H purine compound of the formula N R15 R2 R3 OH or a pharmaceutically acceptable salt or solvate thereof as whereindescribed R1 is H, C1-C6 alkyl or fluorenyl, said C1-C6 alkyl being optionally substituted by 1 or 2 substituents each independently selected from phenyl and naphthyl, said phenyl and naphthyl being optionally substituted by C1-C6 alkyl, C1-C6 alkoxy, halo or cyano; (A) R2 is H or C1-C6 alkyl, R15 is H or C1-C6 alkyl, and X is either (i) unbranched C2-C3 alkylene optionally substituted by C1-C6 alkyl or C3-C8 cycloalkyl, or (ii) a group of the formula: -(CH2)nw-(CH2)n- where W is C5-C7 cycloalkylene optionally substituted by C1-C6 alkyl, n is 0 or 1 and p is 0 or 1, or (B) R15 is H or C1-C6 alkyl, and R2 and X, taken together with the nitrogen atom to which they are attached, represent azetidin-3-yl, pyrrolidin-3-yI, piperidin-3-yl, piperidin-4-yl, homopiperidin-3-yI or homopiperidin-4-yl, each being optionally substituted by C1-C6 alkyl, or (C) R2 is H or C1-C6 alkyl, and R15 and X, taken together with the nitrogen atom to which they are attached, represent azetidin-3-yl, pyrrolidin-3-yl, piperidin-3-yl, piperidin-4-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C1-C6 alkyl; either, R3 and R4, taken together with the nitrogen atom to which they are attached, represent azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, homopiperidinyl or homopiperazinyl, each being optionally substituted on a ring nitrogen or carbon atom by C1-C6 alkyl or C3-C8 cycloalkyl and optionally substituted on a ring carbon atom not adjacent to a ring nitrogen atom by -NR6R7, or, R3 is H, C1-C6 alkyl, C3-C8 cycloalkyl or benzyl and R4 is (a) azetidin-3-yl, pyrrolidin-3-yl, piperidin-3-yl, piperidin-4-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C1-C6 alkyl, C3-C8 cycloalkyl, phenyl, benzyl or het, or (b) -(C2-C6 alkylene)-R8, (c) -(C1-C6 alkylene)-R13, or (d) C1-C6 alkyl or C3-C8 cycloalkyl; R5 is CH2OH or CONR14R14; R6 and R7 are either each independently H or C1-C6 alkyl or, taken together with the nitrogen atom to which they are attached, represent azetidinyl, pyrrolidinyl or piperidinyl, said azetidinyl, pyrrolidinyl and piperidinyl being optionally substituted by C1-C6 alkyl; R8 is (i) azetidin-1-yl, pyrroIidin-1-yl, piperidin-1-yl, morpholin-4-yl, piperazin-1-yl, homopiperidin-1-yl, homopiperazin-1-yl ortetrahydroisoquinolin-1-yl, each being optionally substituted on a ring carbon atom by C1-C6 alkyl, C3-C8 cycloalkyl, phenyl, C1-C6 alkoxy-(C1-C6 alkyl, R9R9N-(C1-C6)-alkyl, fluoro-C1- C6)-alkyl, -CONR9R9, -COOR9 or C2-C6 alkanoyl, and optionally substituted on a ring carbon atom not adjacent to a ring nitrogen atom by fluoro-(C1-C6)-alkoxy, halo, -OR9, cyano, -S(0)mR10, -NR9R9, -S02NR9R9, ~NR9C0R10 or-NR8S02R10, and said piperazin-1-yl and homopiperazin-1-yl being optionally substituted on the ring nitrogen atom not attached to the C2-C6 alkylene group by CrC6 alkyl; , phenyl, C1-C6 alkoxy-(C2-C6)-alkyl, R9R9N-(C2-C6)-alkyl, fluoro-(C1-C6)-alkyl, C2-C6 alkanoyl, -COOR10, C3-C8 cycloalkyl, -S02R10, -S02NR9R9 or-CONR9R9, or . (ii) NR11R12; R9 is H, C1-C6 alkyl, C3-C8 cycloalkyl or phenyl; R10 is C1-C6 alkyl, C3-C8 cycloalkyl or phenyl; R11 is H, C1-C6 alkyl, C3-C8 cycloalkyl or benzyl
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