Composite bone marrow graft material comprising a porous biocompatible implantable matrix and clot material

摘要

A composite bone marrow graft material comprising a porous biocompatible implantable matrix and clot material. The composite bone marrow graft material has an enriched population of progenitor cells obtained by flowing a volume of bone marrow aspirate through a comparatively smaller volume of the implantable matrix so that the progenitor cells from the bone marrow aspirate are selectively adhered to the surface of the matrix. The clot material comprises a blood clot, a bone marrow clot, platelet gel, platelet concentrate, fibrin clot material and fibrin glue. Also disclosed are a method and a kit of preparing the composite bone marrow graft material.