Genes whose expression is increased in response to stimulation by corticotropin-releasing hormone

摘要

An in vitro method for identifying a compound capable of altering the CRH signalling response in a cell, the method comprises: a) contacting the cell with CRH in the presence and absence of the compound; b) determining the amount of at least one protein that modulates corticotrophin releasing hormone (CRH) signalling in the cell; and c) comparing the amount of the protein in the presence or absence of the compound; whereby the protein that modulates CRH signalling consists of SEQ ID NO:28.