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Chandran, V., Ravi

机译:钱德拉·V·拉维

摘要

The present invention is directed to a prodrug comprised of an amino acid bonded to a medicament or drug having a hydroxy, amino, carboxy or acylating derivative thereon. The prodrug has the same utility as the drug from which it is made, but it has enhanced therapeutic properties. In fact, the prodrugs of the present invention enhance at least two therapeutic qualities, as defined herein. The present invention is also directed to pharmaceutical compositions containing same.
机译:本发明涉及一种前药,该前药由结合到其上具有羟基,氨基,羧基或酰化衍生物的药物或药物的氨基酸组成。该前药与制成它的药物具有相同的效用,但是具有增强的治疗性能。实际上,如本文所定义,本发明的前药增强了至少两种治疗质量。本发明还涉及包含其的药物组合物。

著录项

  • 公开/公告号ZA200600660B

    专利类型

  • 公开/公告日2007-04-25

    原文格式PDF

  • 申请/专利权人 SIGNATURE R&D HOLDINGS LLC.;

    申请/专利号ZA20060000660

  • 发明设计人 CHANDRAN V. RAVI;

    申请日2005-01-23

  • 分类号A61K;C07K5/06;C07K7/64;

  • 国家 ZA

  • 入库时间 2022-08-21 20:56:03

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