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idrossammati as inhibitors of histone deacetilasi and pharmaceutical formulations, which shall contain
idrossammati as inhibitors of histone deacetilasi and pharmaceutical formulations, which shall contain
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机译:依德沙替米作为组蛋白去乙酰基酶抑制剂和药物制剂,应含有
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摘要
Compounds of structure (I) having histone deacetylase (HDAC) inhibitor activity are described. The compounds are chemically characterised by the presence of hydroxamic acid, with zinc as chelator, and an aromatic nucleus connected by a linker in which either a bicyclic aromatic system or a piperidino ring are present.
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