COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES

摘要

Method and compositions for treating a patient having a neurological diseaseor disorder, such as stroke, head trauma, spinal cordinjury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage,epilepsy, anxiety, neuropsychiatric or cognitive deficitsdue to ischemia or hypoxia such as those that frequently occur as aconsequence of cardiac surgery under cardiopulmonary bypass,or neurodegenerative diseases such as Alzheimer's Disease, Huntington'sDisease, Parkinson's Disease, or amyotrophic lateral sclerosis(ALS).