PROPHYLACTIC OR THERAPEUTIC AGENT FOR CEREBRAL ISCHEMIA OR CEREBRAL ISCHEMIC REPERFUSION INJURY IN STROKE

摘要

Disclosed is a prophylactic or therapeutic agent for cerebral ischemia injury or cerebral ischemic reperfusion injury occurring in stroke such as cerebral infarction or cerebral hemorrhage, which develops its efficacy through a mechanism different from those of conventional ones and can be administered over a long period. The prophylactic or therapeutic agent comprises 6-fluoro-2',5'-dioxospiro[chroman-4,4'-imidazolidine]-2- carboxamide as an active ingredient. Particularly preferably, the compound is fidarestat, which is an optically resolved form having a (2S,4S) configuration.