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METHODS FOR IDENTIFYING A PATIENT AS A CANDIDATE FOR TREATMENT WITH A LONG ACTING BETA AGONIST AND FOR PREDICTING A PATIENT'S RESPONSE TO LONG ACTING BETA2 AGONIST THERAPY BY ANALYSING POLYMORPHISMS IN THE BETA2-ADRENERGIC RECEPTOR GENE
METHODS FOR IDENTIFYING A PATIENT AS A CANDIDATE FOR TREATMENT WITH A LONG ACTING BETA AGONIST AND FOR PREDICTING A PATIENT'S RESPONSE TO LONG ACTING BETA2 AGONIST THERAPY BY ANALYSING POLYMORPHISMS IN THE BETA2-ADRENERGIC RECEPTOR GENE
The invention relates to a method for identifying a patient as a candidate for treatment with a long acting beta agonist comprises isolating a biological sample from a patient and identifying the presence or absence of at least one haplotype C in the beta2 -adrenergic receptor gene. The presence of at least one haplotype C in a patient sample indicates that patient is a good candidate for treatment. For example, the patient may have a respiratory disease, preferably an obstructive airway disease, and most preferably, COPD or asthma. The invention also related to a method for predicting an asthma patient's response to long acting beta2 agonist therapy comprising detecting polymorphisms in the beta2-adrenergic receptor gene.
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