首页> 外国专利> DUAL BINDING SITE ACETYLCHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

DUAL BINDING SITE ACETYLCHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

机译:双结合位乙酰胆碱酯酶抑制剂治疗阿兹海默氏病

摘要

A family of compounds of formula (I) wherein: X is one of the following radicals: which behaves as dual site acetyl-cholinesterase inhibitors and which are especially useful for the treatment of cognitive disorders as senile dementia, cerebrovascular dementia, mild cognition impairment, attention deficit disorder, and/or neurodegenerative dementing disease with aberrant protein aggregations as specially Alzheimer's disease, Parkinson disease, ALS, or prion diseases, as Creutzfeldt-Jakob disease or Gerst-mann-Straussler-Scheiner disease.
机译:式(I)的化合物家族,其中:X是以下基团之一:充当双位乙酰胆碱酯酶抑制剂,并且特别适用于治疗认知障碍,如老年性痴呆,脑血管性痴呆,轻度认知障碍,注意缺陷障碍和/或神经退行性痴呆疾病,其中包括异常的蛋白质聚集,特别是阿尔茨海默氏病,帕金森氏病,ALS或病毒病,例如Creutzfeldt-Jakob病或Gerst-mann-Straussler-Scheiner病。

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