METHODS FOR MODULATING PPAR ACTIVITY TO TREAT DISEASES CAUSED BY MUTATIONS IN THE CFTR GENE

摘要

This invention features methods for treating diseases associated with mutations in the CFTR gene by administering PPAR agonists, specifically PPARϜ, PPARα, and PPARδ agonists, PPAR inducers, and/or antioxidants. Also disclosed are screening methods for identifying therapeutically useful candidate compounds.