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SPHERON COMPONENTS USEFUL IN DETERMINING COMPOUNDS CAPABLE OF TREATING SYMPTOMS OF ALZHEIMER'S DISEASE, TREATMENTS AND ANIMAL MODELS PRODUCED THEREFROM
SPHERON COMPONENTS USEFUL IN DETERMINING COMPOUNDS CAPABLE OF TREATING SYMPTOMS OF ALZHEIMER'S DISEASE, TREATMENTS AND ANIMAL MODELS PRODUCED THEREFROM
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机译:球蛋白成分,可用于确定可用于治疗由此引发的阿尔希默病,治疗和动物模型症状的化合物
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摘要
The present invention relates to protein components of spherons that are useful for identifying compounds capable of preventing and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to the compounds identified by the methods, and methods of treating and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to methods of making an Alzheimer's Disease or dementia associated with cerebral amyloidosis animal model or test animal, the animal model produced therefrom, and to a method of using the animal model to screen for effective therapies.
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