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Spheron components useful in determining compounds capable of treating symptoms of Alzheimers disease, and treatments and animal models produced therefrom
Spheron components useful in determining compounds capable of treating symptoms of Alzheimers disease, and treatments and animal models produced therefrom
The present invention relates to protein components of spherons that are useful for identifying compounds capable of preventing and/or ameliorating symptoms of Alzheimers Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to the compounds identified by the methods, and methods of treating and/or ameliorating symptoms of Alzheimers Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to methods of making an Alzheimers Disease or dementia associated with cerebral amyloidosis animal model or test animal, the animal model produced therefrom, and to a method of using the animal model to screen for effective therapies.
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