METHODS OF PREPARING A CRYSTALLINE FORM OF 7-(4-CHLOROBUTOXY)-3,4-DIHYDRO-2(1H)-QUINOLINONE AND THE USE THEREOF IN THE SYNTHESIS OF ARIPIPRAZOLE

摘要

The present invention relates to methods of preparing a highly pure crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-2(1H)-quinolinone, which is a chemical intermediate useful in the preparation of Aripiprazole thereof in high quality and yield, and provides data that characterizes the crystalline form of 7-(4-chlorobutoxy)-3,4-dihydro-(1H)-quinolinone.