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TREFOIL FACTOR 3 (TFF3) AS A TARGET FOR ANTI-CANCER THERAPY
TREFOIL FACTOR 3 (TFF3) AS A TARGET FOR ANTI-CANCER THERAPY
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机译:三叶因子3(TFF3)作为抗癌治疗的目标
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摘要
The present invention is directed to methods of treating and preventing cancer, such as cancer characterized by differential expression of trefoil factor 3 (TFF3). The methods include administering to a patient an agent that modulates TFF3 activity or expression. The present invention is further directed to reducing the physiological effects of TFF3 expression in cells, including inhibiting cell motility and resistance to apoptosis. Oligonucleotides and antibodies that can modulate expression or activity of TFF3 are also provided.
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