HBx PEPTIDES, CAPABLE OF ELICITING A PROMISCUOUS IMMUNODOMINANT CD4+ RESPONSE DIRECTED AGAINST HBV

摘要

The present invention relates to HBx peptides, and analogues and sub-fragments thereof, which are useful for eliciting a CD4+ response against HBV, and more a CD4+ promiscuous immunodominant response. The present invention also relates to mutant peptides, which have lost their capacity of eliciting a CD4+ response, and which are useful for prognosis a predisposition to develop a HCC.