RENAL CELL CARCINOMA-ANTIGEN G250-DERIVED PEPTIDE ELICITING BOTH CD4+ AND CD8+ T-CELL RESPONSES

摘要

PPROBLEM TO BE SOLVED: To provide a renal cell carcinoma-antigen G250-derived peptide eliciting both CD4+ and CD8+ T-cell responses. PSOLUTION: The peptide has a specific amino acid sequence and is derived from a G250 tumor antigen that is frequently expressed on immunogenic tumors such as renal cell carcinoma. The particular peptide is selected from the capability to elicit both the CD4+ and the CD8+ T-cell responses against cells expressing the G250 antigen. PCOPYRIGHT: (C)2004,JPO