METHODS FOR IDENTIFYING A PATIENT AS A CANDIDATE FOR TREATMENT WITH A LONG ACTING BETA AGONIST AND FOR PREDICTING A PATIENT'S RESPONSE TO LONG ACTING BETA 2 AGONIST THERAPY BY ANALYSING POLYMORPHS IMS IN THE BETA 2 -ADRENERGIC RECEPTOR GENE

摘要

The invention relates to a method for identifying a patient as a candidate for treatment with a long acting beta agonist comprises isolating a biological sample from a patient and identifying the presence or absence of at least one haplotype C in the beta2 -adrenergic receptor gene. The presence of at least one haplotype C in a patient sample indicates that patient is a good candidate for treatment. For example, the patient may have a respiratory disease, preferably an obstructive airway disease, and most preferably, COPD or asthma. The invention also related to a method for predicting an asthma patient's response to long acting beta2 agonist therapy comprising detecting polymorphisms in the beta2-adrenergic receptor gene.