The extract of Green Tea having inhibition activity for urease of Helicobacter pylori and the health functional food using thereof

摘要

Provided are a green tea extract comprising polyphenol ingredient of green tea and a health food using the same, which can be used for treating or preventing various stomach-related diseases including gastric cancer, gastric ulcer, or gastritis generated by helicobacter pyroli. The green tea extract comprises polyphenol ingredient having inhibitory effect to urease activity of helicobacter pylori. The polyphenol ingredient comprises (-)-epicatechin(EC), (-)-epigallocatechin(EGC), (-)-epicatechin 3-galate(ECG), and (-)-epigallocatechin 3-O-gallate(EGCG). The polyphenol ingredient is obtained by extracting dried leaf of green tea with 20-40% ethanol at 60-70 deg.C for 6-8 hours, recovering 70% ethanol-developed liquid obtained by developing the extract with porous resin column, and then decompression-concentrating and extracting the developed liquid, and finally isolating the extract by high performance liquid chromatography(HPLC).