首页> 外国专利> A MARKER FOR SELECTING RADIATION-SENSITIVE HEPATOCELLULAR CARCINOMA CELL LINES, KIT AND MICROARRAY COMPRISING THE SAME AND METHOD FOR SELECTING RADIATION-SENSITIVE HEPATOCELLULAR CARCINOMA CELL LINES USING THE MARKER

A MARKER FOR SELECTING RADIATION-SENSITIVE HEPATOCELLULAR CARCINOMA CELL LINES, KIT AND MICROARRAY COMPRISING THE SAME AND METHOD FOR SELECTING RADIATION-SENSITIVE HEPATOCELLULAR CARCINOMA CELL LINES USING THE MARKER

机译:一种用于选择辐射敏感性肝细胞癌细胞系,工具包和微阵列的标记器,以及使用该标记器选择辐射敏感性肝细胞癌细胞系的方法

摘要

A marker for selecting radiation-sensitive hepatocellular carcinoma cell lines, a kit and microarray comprising the same marker and a method for selecting radiation-sensitive hepatocellular carcinoma cell lines by using the same marker are provided to increase therapeutic effects of radiation on the hepatocellular carcinoma by controlling target genes within cells. The marker for selecting radiation-sensitive hepatocellular carcinoma cell lines contains at least one gene selected from genes listed in table 4, and further contains at least one gene selected from genes listed in table 5. The marker containing the genes listed in table 6 shows increase of expression in the radiation-resistant hepatocellular carcinoma cell lines and decrease of expression in radiation-sensitive hepatocellular carcinoma cell lines. The kit and microarray for selecting radiation-sensitive hepatocellular carcinoma cell lines comprise the marker.
机译:提供了用于选择放射敏感性肝细胞癌细胞系的标志物,包括该标志物的试剂盒和微阵列以及通过使用相同的标志物选择放射敏感性肝细胞癌细胞系的方法,以通过以下方式增强放射线对肝细胞癌的治疗效果:控制细胞内的靶基因。用于选择放射敏感性肝细胞癌细胞系的标记物包含选自表4所列基因的至少一种基因,并且进一步包含选自表5所列基因的至少一种基因。包含表6所列基因的标记物显示出增加。辐射抗性肝癌细胞系中表达的降低和辐射敏感性肝细胞癌细胞系中表达的降低。用于选择辐射敏感性肝细胞癌细胞系的试剂盒和微阵列包含标记。

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