Solid dosage forms containing clathrates of the steroidal sex hormone ethinyl estradiol

摘要

PCT No. PCT/EP95/02656 Sec. 371 Date Apr. 2, 1997 Sec. 102(e) Date Apr. 2, 1997 PCT Filed Jul. 10, 1995 PCT Pub. No. WO96/02277 PCT Pub. Date Feb. 1, 1996A method and pharmaceutical compositions are disclosed for reducing oxidative degradation of 17 alpha -ethinylestradiol comprising combining the estradiol with an effective amount of cyclodextrin, thus forming a cyclodextrin clathrate of the steroid.