CD4 + CD25 + REGULATORY T CELLS SPECIFIC FOR HEMATOPOIETIC CELL TRANSPLANT AND IMMUNE TOLERANCE

摘要

The invention relates to a pharmaceutical composition comprising CD4 + CD25 + regulatory T cells specific for at least one minor histocompatibility antigen or at least one surface protein, as well as non-embryonic hematopoietic stem cells carrying at least said antigen. or said surface protein. Such a composition can be used as a drug to increase the immune tolerance of a histocompatible host.