MEDICINAL COMPOSITION CONTAINING HLA-A24 MOLECULE-BINDING PEPTIDE ORIGINATING IN PARATHYROID HORMONE-RELATED PROTEIN

摘要

PPROBLEM TO BE SOLVED: To provide a medicinal composition that enables peptide-based immunotherapy of a cancer patient having a bone metastasis. PSOLUTION: The medicinal composition for treating or preventing cancers (excluding prostatic cancer) contains a peptide binding to an HLA-A24 molecule and originating in a parathyroid hormone-related protein or its derivative having functionally the same properties. The medicinal composition induces a PTH-rP peptide-specific and cancer-reactive CTL in various cancer type HLA-A24 molecule positive cancer patients and treats or prevents cancers. The medicinal composition enables peptide-based immunotherapy of many cancer patients, above all of a cancer patient having a bone metastasis. PCOPYRIGHT: (C)2009,JPO&INPIT