首页> 外国专利> METHOD FOR MEASURING CANCER CELL GROWTH INHIBITORY ACTION AND INFLAMMATORY CYTOKINE INHIBITORY ACTION OF LACTIC ACID BACTERIUM AND SUBSTANCE DERIVED FROM LACTIC ACID BACTERIUM

METHOD FOR MEASURING CANCER CELL GROWTH INHIBITORY ACTION AND INFLAMMATORY CYTOKINE INHIBITORY ACTION OF LACTIC ACID BACTERIUM AND SUBSTANCE DERIVED FROM LACTIC ACID BACTERIUM

机译:乳酸菌和来源于乳酸菌的物质的癌细胞生长抑制作用和炎性细胞因子抑制作用的测定方法

摘要

PROBLEM TO BE SOLVED: To provide a method for easily measuring the antitumor effect of lactic acid bacterium, a method for screening a lactic acid bacterium having an antitumor effect by using the method, a method for easily measuring an anti-inflammatory cytokine effect of lactic acid bacterium and a method for screening a lactic acid bacterium having an inflammatory cytokine inhibitory effect by using the method.;SOLUTION: The method for measuring a cancer cell growth inhibitory action of lactic acid bacterium comprises culturing U937 cells (monocytic blastoid derived from histiocytic lymphoma patient) and assaying the presence of proliferation of the U937 cells and/or the degree of proliferation. The method for screening a lactic acid bacterium having a cancer cell growth inhibitory action comprises using the method. The method for measuring the inflammatory cytokine inhibitory action of lactic acid bacterium comprises culturing U937 cells in the presence of the lactic acid bacterium and inflammatory cytokine and assaying the presence of proliferation of the 937 cells and/or the degree of proliferation. The method for screening a lactic acid bacterium having an inflammatory cytokine inhibitory action comprises using the method.;COPYRIGHT: (C)2008,JPO&INPIT
机译:解决的问题:为了提供一种容易测量乳酸菌的抗肿瘤作用的方法,一种使用该方法筛选具有抗肿瘤作用的乳酸菌的方法,一种容易测量乳酸的抗炎细胞因子作用的方法。酸细菌和使用该方法筛选具有炎性细胞因子抑制作用的乳酸菌的方法;解决方案:测量乳酸菌对癌细胞生长的抑制作用的方法包括培养U937细胞(源自组织细胞性淋巴瘤的单核细胞胚样)患者),并检测U937细胞的增殖情况和/或增殖程度。筛选具有癌细胞生长抑制作用的乳酸菌的方法包括使用该方法。用于测量乳酸菌的炎性细胞因子抑制作用的方法包括在乳酸菌和炎性细胞因子的存在下培养U937细胞,并测定937细胞的增殖和/或增殖程度。筛选具有炎性细胞因子抑制作用的乳酸菌的方法包括使用该方法。COPYRIGHT:(C)2008,JPO&INPIT

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