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Naphthyridine derivatives, their preparation and their use as phosphodiesterase isoenzyme 4 (PDE4) inhibitors

机译:萘啶衍生物,其制备及其作为磷酸二酯酶同工酶4(PDE4)抑制剂的用途

摘要

The invention relates to compounds of formula I in free or salt form, where RSUP1 /SUPis a monovalent aromatic group having up to 10 carbon atoms, and RSUP2 /SUPis a cycloaliphatic group having up to 8 ring carbon atoms. Compositions containing them, methods for their preparation and their use as pharmaceuticals are also described.
机译:本发明涉及游离形式或盐形式的式I化合物,其中R 1 是具有至多10个碳原子的单价芳族基团,R 2 是脂环族基团具有最多8个环碳原子。还描述了包含它们的组合物,其制备方法及其在药物中的用途。

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