N- acetyl lacto Sami nil - cello-oligosaccharide derivatives and a method of manufacturing the same

摘要

PROBLEM TO BE SOLVED: To provide a non-natural type new cellooligosaccharide derivative, and to provide a method for producing the same.;SOLUTION: This method for producing the new cellooligosaccharide derivative, an N-acetyllactosaminyl-cellooligosaccharide derivative, comprises the following process: using a cellooligosaccharide or a derivative thereof as a saccharide receptor and an oxazoline derivative of N-acetyllactosamine as a saccharide donor, a chitinase is subjected to them under alkaline conditions to obtain the objective N-acetyllactosaminyl-cellooligosaccharide derivative where N-acetyllactosamine is transferred via a β-1,4-linkage to the non-reduced terminal of the cellooligosaccharide or the derivative thereof; wherein it is preferable that the chitinase (preferably, Bacillus-derived one) be subjected to both the saccharide receptor and donor under the condition of pH 8-10.;COPYRIGHT: (C)2003,JPO