Gene interaction estimation apparatus gene interaction estimation method, and gene interaction estimation program, as well as binding sites estimation device binding sites estimation method, and binding sites estimation program,

摘要

PPROBLEM TO BE SOLVED: To provide a method for estimating genetic interaction capable of estimating genetic interaction highly precisely while using a DNA microarray. PSOLUTION: The method for estimating genetic interaction is performed by fusing three independent estimation methods, first filtering processing using correlation of expression data, second filtering processing to be a totally new method for estimating a binding site, and third filtering processing using the gene expression data with experimentation operation added thereto. As the second filtering processing, with respect to a pair of a gene (a) and a gene (b) of a group of genes B to be the prescribed number of higher order genes in which an absolute value of correlation coefficient with the gene (a) is large, window similarity to be a sum of similarities at each position when a maximum value of the similarity of character strings of a prescribed length (k) which have approximate starting positions included in the windows is defined as the similarity at the position is calculated. PCOPYRIGHT: (C)2008,JPO&INPIT