Preventive and therapeutic agents for dry eye in chronic graft-versus-host disease

摘要

The present invention provides a pharmaceutical composition for the prevention and treatment of dry eye in chronic graft-versus-host disease (cGVHD) after hematopoietic stem cell transplantation. That is, peripheral blood stem cell transplantation, cord blood transplantation, bone marrow transplantation and the like containing N- (3,4-dimethoxycinnamoyl) anthranilic acid (generic name: tranilast) or a pharmacologically acceptable salt thereof as an active ingredient The present invention provides a pharmaceutical composition for the prevention and treatment of dry eye in GVHD that occurs after transplantation of hematopoietic stem cells.