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The three-dimensionally crosslinked superabsorbent γ-polyglutamic acid hydrogels biodegradable stable, and their preparation
The three-dimensionally crosslinked superabsorbent γ-polyglutamic acid hydrogels biodegradable stable, and their preparation
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机译:三维可交联的可生物降解的高吸收性γ-聚谷氨酸水凝胶及其制备方法
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摘要
The present invention relates to a method for the production of a stable biodegradable, high water absorbable gamma -polyglutamic acid ( gamma -PGA) hydrogel by directly cross-linking (A) a gamma -polyglutamic acid ( gamma -PGA), a gamma -polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof; and/or (B) a microbial culture broth containing a gamma -polyglutamic acid ( gamma -PGA), a gamma -polyglutamate, or a mixture thereof, and optionally a polysaccharide containing a carboxylic and/or carboxylate group, an amino acid, or a mixture thereof, with a cross-linker comprising a compound having three or more functional groups or a mixture of a compound having three or more functional groups and a compound having two functional groups, wherein each of the functional groups can react with a carboxylic group (-COOH), carboxylate group (-COO-), aldehyde group (-CHO), hydroxyl (-OH), carbonyl group (-CO), sulfone group (-SO2), amino group (-NH2) or nitro group (-NO2), or a mixture thereof. ??The present invention further relates to a stable biodegradable, high water absorbable gamma -polyglutamic acid ( gamma -PGA) hydrogel and its uses.
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