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PROTEASOMAL PEPTIDASE ACTIVITY AND THE USE THEREOF IN CLINICAL APPLICATIONS
PROTEASOMAL PEPTIDASE ACTIVITY AND THE USE THEREOF IN CLINICAL APPLICATIONS
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机译:蛋白酶体肽酶活性及其在临床应用中的用途
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摘要
Provided herein are methods for the diagnosis, prognosis, or management of hematological disorders and other diseases using the proteasome activity levels determined in acellular body fluids or cell-containing samples. Also provided are methods of monitoring treatment with proteasome inhibitors through assaying proteasome activity in acellular body fluids. Further provided are methods of predicting response to therapy in certain populations of leukemia patients.
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