Transcriptional Termination of Transgene Expression Using Host Genomic Terminators

摘要

The present invention relates to a method for expressing a transgene in a host cell that permits transcriptional termination of the transgene to occur without having to rely on a functional termination site in the DNA used for the transformation. Additional 3′ regulatory sequences and 3′ end processing enhancing sequences and/or structures can be present in the transformation vector or as a fusion with the transgene of interest.