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Assays and methods to detect beta-secretase and its activity in body fluids and tissue extracts

机译:检测β-分泌酶及其在体液和组织提取物中的活性的测定和方法

摘要

Methods and assays for detecting β-secretase (BACE-1) activity in body fluids or tissue extracts from individuals, particularly individuals who have Alzheimer's disease, are disclosed. A truncated form of BACE-1 was isolated that can be used as a biomarker for Alzheimer's disease.
机译:公开了用于检测来自个体,特别是患有阿尔茨海默氏病的个体的体液或组织提取物中的β-分泌酶(BACE-1)活性的方法和测定法。分离出截短形式的BACE-1,可以用作阿尔茨海默氏病的生物标记。

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