首页> 外国专利> SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS

SULFAMIDE AND SULFAMATE DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS

机译:硫酰胺和硫酸盐衍生物作为组蛋白十足抑制剂

摘要

This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I), and racemic and scalemic mixtures, diastereomers and enantiomers thereof: or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt, prodrug or complex thereof, wherein Y, L, Z, W, M, Ra, Rb and Rc are as defined in the specification.
机译:本发明涉及用于抑制组蛋白脱乙酰基酶的化合物。更具体地,本发明提供了式(I)的化合物,及其外消旋和垢混合物,非对映异构体和对映异构体: <图像文件=“ US20070293530A1-20071220-C00001.GIF” he =“ 18.20mm” id =“ EMI-C00001” imgContent =“ chem” imgFormat =“ GIF” wi = “ 56.47mm” /> 或其N-氧化物,水合物,溶剂化物,药学上可接受的盐,前药或复合物,其中Y,L,Z,W,M,R a ,R b 和R c 如规范中所定义。

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