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Swine Cell For Xenotransplantation, Method of Selecting the Same and Swine For Xenotransplantation
Swine Cell For Xenotransplantation, Method of Selecting the Same and Swine For Xenotransplantation
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机译:异种移植的猪细胞,异种移植的选择方法
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摘要
The invention presents a swine cell not expressing α-1,3-galactosyl transferase and expressing human complement inhibitor and/or human N-acetyl glucosaminyl transferase III; a method of selecting the same; and a swine for xenotransplantation. The swine for xenotransplantation of the invention is very useful in inhibiting the acute rejection characteristic to xenotransplantation because it does not express α-Gal antigen but inhibits the progress of a complement reaction, if unexpectedly induced, and/or expresses little xenoantigen other than α-Gal antigen.
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