HYBRID HEMODIALYSIS ACCESS GRAFTS OR A HYBRID FEMORAL ARTERY BYPASS GRAFT AND SYSTEMS AND METHODS FOR PRODUCING OR MODIFYING THE SAME

摘要

Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external flow loop system coupled to a specimen holder, where the pressure/flow loop subsystem is capable of adjusting at least two dynamic conditions in the specimen holder or a diameter of a specimen in the specimen holder. Embodiments of methods can prepare a hybrid hemodialysis access graft or a hybrid femoral artery bypass graft intended for implantation into a mammal by placing the hybrid graft in a system embodiment according to the invention prior to implantation of the hybrid graft into the mammal.