首页>
外国专利>
Method of delivering a bioactive agent with porous β-tricalcium phosphate granules
Method of delivering a bioactive agent with porous β-tricalcium phosphate granules
展开▼
机译:用多孔β-磷酸三钙颗粒递送生物活性剂的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A porous β-tricalcium phosphate material for bone implantation is provided. The multiple pores in the porous TCP body are separate discrete voids and are not interconnected. The pore size diameter is in the range of 20-500 μm, preferably 50-125 μm. The porous β-TCP material provides a carrier matrix for bioactive agents and can form a moldable putty composition upon the addition of a binder. Preferably, the bioactive agent is encapsulated in a biodegradable agent. The invention provides a kit and an implant device comprising the porous β-TCP, and a bioactive agent and a binder. The invention also provides an implantable prosthetic device comprising a prosthetic implant having a surface region, a porous β-TCP material disposed on the surface region and optionally comprising at least a bioactive agent or a binder. Methods of producing the porous β-TCP material and inducing bone formation are also provided.
展开▼