Carboxamidas and tiocarboxamidas employed in the fight against the undesirable microorganisms and in the treatment of Seeds and plants transgu00c9nicas, compositions containing them, and Method for obtaining same and a process for the preparation of these carboxamidas and intermediary d E s

摘要

Several procedures to obtain these products and their use for Combating undesirable Microorganisms, as well as Intermediates.Claim 1: a compound of formula (1), in which X is o (Oxygen) or s (Sulfur); M is a Ring of phenyl, thiophene, pyridine, pyrimidine and pyrazine or substituted pyridazine hydrochloride, in each case, by means of a thiazole Ring R1 or replaced R1 R2; sign Qualifications Hydrogen, Fluorine, Chlorine, Methyl Iso propylMethylthio or trifluoromethyl; R2 is Hydrogen, Methyl, or methylthio trifluoromethyl; Q means a direct link, alquileno C1 - C2 - 4, alquenileno 4, o, S, so, SO2 or NR1; R3 is Hydrogen, alkyl c1-4 alkoxy, c1-4 alkyl Alquiltio C1 C1 - 4 - 4 - Rent alquenilo C2, C2 - 8 - 8 alquinilo, Hal Ogeno alkyl halogen - alquenilo C1 - C2 - 6 6Halogen - alquinilo C2 or C3 cycloalkyl - 6 - 6; Z means Z1, Z2, Z3, Z4, Z5 and Z6; Z1 represents a phenyl substituted, Optionally, one to five times by the same or different substituents; Z2 means substituted pyridinyl Optionally, one to three times by substituents, ID u00e9nticos or different; Z3 Means or bicicloalquilo cycloalkyl substituted in each caseOptionally, one or several times by the same or different substituents, the group formed by Halogen, alkyl and / or - (cr4r5) msir6r7r8; Z4 means Rent C2 - not 20 or c1-20 alkyl substituted means replaced once or several times by the same or different Substituent Group Composed by Alquiltio, halogen, alkoxy alquilsulfonilo alquilsulfinilo,,,By alquilamino, dialquilamino, halogen - Alquiltio, halogenoalquilsulfinilo, alquilsulfonilo Halogen Halogen, alkoxy, halogen - alquilamino, dialquilamino halogen -, - and - 6 pp. sir6r7r8 cycloalkyl substituted cycloalkyl, being the party, for its part, OPC Ionalmente, once or several times,Identical or different substituents on the alkyl group formed by Halogen C1 - and C2 - 4; Z5 means alquenilo 20 or alquinilo c2-20 replaced in each case, Optionally, one or several times by the same or different substituents, the group formed by Halogen, Alquiltio, alquilsu Lfinilo, alquilsulfonilo alquilamino, alkoxy, halogen, dialquilamino, Alquiltio,- alquilsulfinilo by Halogen, halogen - alquilsulfonilo by Halogen, alkoxy, halogen - alquilamino, halogen - dialquilamino, sir6r7r8 and cycloalkyl - C3 - 6 may be replaced by the cycloalkyl, Optionally, one or several times,By identical or different substituents of the Group comprising Halogen and c1-4 alkyl; Z6 means a Ring with three to Seven members, saturated or unsaturated, SUBSTITUTED, Optionally, one or several times, which contains a Silicon Atom as a member of the ring,Then q represents a direct link or alquileno c1-4 alkyl; R4 is Hydrogen or c1-4 alkyl; R5 is Hydrogen or c1-4, M = 0, 1, 2 or 3; R6 and R7 are independently Hydrogen, alkyl, alkoxy, C1 - 8 - 8 - alkoxy C1, C1 4 - c1-4 alkyl, Alquiltio c1-4 alkyl C1-4 alkyl or Halogen C1 - 6; R8 means Hydrogen, alkyl alkoxy C1 C1 - 8 - 8C1-4 alkoxy c1-4 alkyl, Alquiltio c1-4 alkyl alquenilo C1 C2 - 4 - 8 - 8 - alquinilo C2 alkyl, halogen C1 - C2 - halogenoalquenilo 6, 6, 6 halogenoalquinilo C2 - C3 - 6, cycloalkyl or means in each case fenilalquilo phenyl or substituted, optionally; or M - Q - Z are, on the whole, 1H - 2.3 - dihidr Inden - or - 4 - ILO, 1,3 - dihydro - 4 - yl - 2 - benzofuran or 13 - dihydro - 4 - 2 - benzotien ILO replaced in each case, Optionally, one to three times by means of the Methyl radical; one A1 A19 until the group of formulas (2); R9 is Hydrogen, halogeno, cyano, Nitro, c1-4 alkyl, c1-4 alkoxy, Alquiltio C1 - C3 - 6 4, cycloalkyl, halogen - Lquilo c1-4 alkoxy, halogen or Halogen C1 - 4 - 4 with Alquiltio C1 - in each case1 to 5 Atoms aminocarbonilo Aminocarbonyl - alkyl or Halogen, c1-4, R10 is Hydrogen, halogeno, cyano, c1-4 alkyl, alkoxy c1-4 or Alquiltio c1-4, R11 is Hydrogen, alkyl c1-4 alkyl, Hydroxy alquenilo C1 - C2 - 4, 6 - 6, cycloalkyl C3 Alquiltio c1-4 alkyl, c1-4 alkoxy, C1 - 4 C1-4 alkyl, halogen c1-4 alkyl, halogen - Alquiltio c1-4 alkyl c1-4,Halogen c1-4 alkoxy c1-4 alkyl with 1 to 5 in each case, halogen Atoms or phenyl; mean R12 and R13, including Hydrogen, halogen, alkyl, c1-4 alkyl or Halogen C1 - 4 with 1 to 5 Halogen Atoms; R14 means halogeno, cyano or c1-4 alkyl or halogen - alkyd ILO c1-4 alkoxy - or Halogen C1 - 4 with, in each case, 1 to 5 Halogen Atoms; R15 and R16 meanIndependently, Hydrogen, halogen, alkyl or Halogen c1-4 alkyl with 1 to 5 c1-4 Halogen Atoms; R17 is Hydrogen, halogen, alkyl or Halogen c1-4 alkyl with 1 to 6 c1-4 Halogen Atoms; R18 is Hydrogen, halogen, Hydroxy alkyl, cyano, C1 - 6, halo Geno c1-4 alkyl or Halogen, halogenoalcoxi C1 - 4 - 4 with Alquiltio C1 - in each case1 to 5 Halogen Atoms; R19 is Halogen, Hydroxy alkyl, cyano, c1-4 alkoxy, c1-4, Alquiltio c1-4 alkyl, halogen c1-4, halogen or halogen - Alquiltio c1-4 alkoxy c1-4 with, in each case, 1 to 5 Halogen Atoms; R20 means Hydrogen, halogeno, cyano, c1-4 alkyl, alkoxy C1 - 4, Alquiltio c1-4 alkyl, halogen c1-4 alkoxy, halogen C1 - 4 with, in each case,1 to 5 of halogen ATOMS, alquilsulfinilo c1-4 or alquilsulfonilo c1-4 alkyl C1 means; R21 - 4 Halogen or alkyl with 1 to 5 c1-4 alkyl Halogen Atoms; R22 is c1-4, Q1 means s (Sulfur), so, SO2 or CH2; p is 0, 1 or R22 radical 2, being identical or differentWhen p is 2; R23 means alkyl or Halogen c1-4 alkyl with 1 to 5 c1-4 alkyl Halogen Atoms; R24 means c1-4 alkyl or Halogen C1 - 4 with 1 to 5 Halogen Atoms; 25 and 26 are independently Hydrogen, halogen, alkyl, amino, C1 - 4 or Halogen C1-4 alkyl with 1 to 5 Halogen Atoms; R27 is Hydrogen, halogen,C1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 Halogen Atoms; R28, R29, independently Hydrogen, halogen, alkyl, amino, Nitro, c1-4 alkyl or Halogen C1 - 4 with 1 to 5 Halogen Atoms; R30 is Hydrogen, halogen, alkyl of C1 - 4 - alkyl or Halogen C1 - 4 with 1 to 5 Halogen Atoms; R31 is Hydrogen, halogen, amino, alquilamino c1-4,Di - (c1-4 alkyl) amino, cyano, c1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 means Halogen Halogen Atoms; R32, c1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 Halogen Atoms; R33 is Hydrogen, halogen, amino, alquilamino di - (c1-4 alkyl, c1-4 alkyl) amino, cyano, C1-4 alkyl or Halogen C1 - 4 with 1 to 5 Halogen Halogen Atoms; R34 means,C1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 Halogen Atoms; R35 is c1-4 alkyl or Halogen, halogen c1-4 alkyl with 1 to 5 Atoms of hydrogen, alkyl or Halogen; R36 means c1-4 alkyl or Halogen; R37 means c1-4 alkyl R38 C1 means; - 4 - alkyl or Halogen C1 - 4 C On 1 to 5 Halogen Atoms; R39 is Hydrogen, halogen,C1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 Halogen Atoms; R40 is Halogen, Hydroxy, c1-4 alkyl, c1-4 alkoxy, Alquiltio c1-4 alkyl, halogen C1 - 4, halogenoalquiltio c1-4 alkoxy - or Halogen C1 - 4 with, in each case, 1 to 5 Halogen Atoms; R41 means Hydrogen, cyano, C1-4 alkyl, halogen c1-4 alkyl with 1 to 5 ATOMS, halogen, alkoxy c1-4 alkyl c1-4,Hydroxy c1-4 alkyl, alquilsulfonilo c1-4, di (c1-4 alkyl) aminosulfonilo, alquilcarbonilo C1 - 6 or fenilsulfonilo or optionally substituted benzoyl; in each case, R42 is Hydrogen, halogen, alkyl or Halogen c1-4 alkyl with 1 to 5 c1-4 R43 Hydrogen Halogen Atoms; means, Halogeno, cyano,C1-4 alkyl or Halogen c1-4 alkyl with 1 to 5 Halogen Atoms; R44 means. Hydrogen, halogen, alkyl or Halogen c1-4 alkyl with 1 to 5 c1-4 alkyl Halogen Atoms; R45 means C1 - 4.