compound or a pharmaceutically acceptable salt or prodrug thereof, method for producing an antibacterial effect on a warm-blooded animal, use of a pharmaceutically acceptable salt or compound, or an in vivo hydrolysable ester thereof, pharmaceutical composition, and, a process for preparing a pharmaceutically acceptable salt or compound or an in vivo hydrolysable ester thereof.

摘要

COMPOUND OR A PHARMACEUTICALLY ACCEPTABLE SALT OR PRODUCT OF THE SAME, A METHOD FOR PROVIDING AN ANTIBACTERIAL EFFECT ON A HOT BLOOD ANIMAL, USE OF A PHARMACEUTICALLY ACCEPTABLE COMPOSITE, OR HYDROATIC HYDROATIC SALT A process for the preparation of a pharmaceutically acceptable compound or salt or an in vivo hydrolyzable ester thereof. wherein R¬ 1¬ is selected from hydrogen, halogen, cyano, optionally substituted methyl; R¬2¬ and R¬3¬ are independently selected from hydrogen, fluorine, chlorine and trifluoromethyl; and R¬5¬ are independently selected from, for example, optionally substituted hydrogen, methyl, (2-4C) alkyl, C (O) R¬6¬ or R¬4¬ and R¬5¬ together with nitrogen at the same time. which they are attached, form an optionally substituted 4- or 5- membered saturated or partially unsaturated heterocyclyl ring or an optionally substituted imidazole ring. Methods for manufacturing the compounds of formula (I), compositions containing them and their use as antibacterial agents are also described.