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androgen deprivation-induced osteoporosis treatment

机译:雄激素剥夺诱导的骨质疏松症治疗

摘要

"TREATMENT OF ANDROGEN PRIVACY-INDUCED OSTEOPOROSIS" The present invention provides methods for reducing the incidence, inhibiting, suppressing, and treating androgen deprivation-induced osteoporosis, bone fractures, and / or bone mineral density (BMD) loss in men. prostate cancer, comprising administering to a male human subject having prostate cancer a toremifene and / or its analog, derivative, isomer, matabolite, pharmaceutically acceptable salt, pharmaceutical, hydrate, N-oxide, or any related combination. The present invention also provides methods for treating, preventing, suppressing, inhibiting, or reducing the incidence of hot flashes, and / or hair loss in an individual, even comprising toremifene and / or its analog, derivative, isomer, etc.
机译:“雄激素引起的骨质疏松症的治疗”本发明提供了减少男性雄激素缺乏引起的骨质疏松症,骨折和/或骨矿物质密度(BMD)损失的发生率,抑制,抑制和治疗的方法。前列腺癌,包括对患有前列腺癌的男性受试者给予托瑞米芬和/或其类似物,衍生物,异构体,代谢产物,药学上可接受的盐,药物,水合物,N-氧化物或任何相关组合。本发明还提供用于治疗,预防,抑制,抑制或减少潮热和/或脱发的发生率的方法,所述个体甚至包含托瑞米芬和/或其类似物,衍生物,异构体等。

著录项

  • 公开/公告号BRPI0515668A

    专利类型

  • 公开/公告日2008-07-29

    原文格式PDF

  • 申请/专利权人 GTX INC;

    申请/专利号BR2005PI15668

  • 申请日2005-09-19

  • 分类号A61K9/14;A61K31/138;

  • 国家 BR

  • 入库时间 2022-08-21 20:08:44

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