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reagents for cancer cell detection, and for cancer diagnosis, cell death inducing agent, and methods for cancer cell detection, cancer diagnosis, and cell death induction in a target cell

机译:用于癌细胞检测,癌症诊断的试剂,细胞死亡诱导剂以及用于靶细胞中癌细胞检测,癌症诊断和细胞死亡诱导的方法

摘要

CANCER CELL DETECTION, AND CANCER DIAGNOSIS REAGENTS, CELL DEATH INDICATOR, AND CANCER DIAGNOSIS, AND CELL CELL DEVELOPMENT INDUCTION METHODS It is intended to provide a reagent to detect cancer cell or cancer diagnosis. More specifically, a cancer cell-containing reagent for detecting a recombinant virus in which a replication cassette having a human telomerase promoter, E1A gene, IRES sequence, and E1B gene in this order is integrated into the E1 region of the vital genome as a labeling cassette. having a gene encoding a tagging protein and a promoter capable of regulating gene expression is integrated into the E3 region of the vital genome.
机译:癌细胞检测,癌症诊断试剂,细胞死亡指示剂,癌症诊断和细胞发育诱导方法本发明旨在提供检测癌细胞或癌症诊断的试剂。更具体地,用于检测重组病毒的含癌细胞的试剂,其中具有人端粒酶启动子,E1A基因,IRES序列和E1B基因的顺序的复制盒被整合到生命基因组的E1区域中作为标记卡带。具有编码标签蛋白的基因和能够调节基因表达的启动子的载体被整合到生命基因组的E3区域中。

著录项

  • 公开/公告号BRPI0516191A

    专利类型

  • 公开/公告日2008-08-26

    原文格式PDF

  • 申请/专利权人 ONCOLYS BIOPHARMA INC;

    申请/专利号BR2005PI16191

  • 申请日2005-09-28

  • 分类号C12Q1/04;A61K35/76;A61K35/761;A61K35/768;A61K38/51;A61K48;A61K49;A61P35;A61P35/02;A61P35/04;A61P43;C12N7;C12N7/01;C12N15/09;C12N15/86;G01N21/78;G01N33/48;G01N33/58;

  • 国家 BR

  • 入库时间 2022-08-21 20:08:43

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