首页> 外国专利> Compounds 4 - imidazolines, Taar ligands; procedure of preparation of these Compounds, Pharmaceutical Composition and Use thereof for treating Depression, anxiety,Attention deficit hyperactivity disorder (ADHD), re Disorders

Compounds 4 - imidazolines, Taar ligands; procedure of preparation of these Compounds, Pharmaceutical Composition and Use thereof for treating Depression, anxiety,Attention deficit hyperactivity disorder (ADHD), re Disorders

机译:化合物4-咪唑啉,Taar配体;这些化合物的制备方法,药物组合物及其在治疗抑郁症,焦虑症,注意缺陷多动障碍(ADHD),重症中的用途

摘要

The invention relates to imidazole derivatives which have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1. The invention also relates to a pharmaceutically-suitable acid-addition salt of the above compound. The invention further relates to a composition comprising an imidazole derivative as described above, or a pharmaceutically-suitable acid-addition salt thereof, and to processes for preparing such compounds.
机译:本发明涉及对痕量胺相关受体(TAAR),特别是对TAAR1具有良​​好亲和力的咪唑衍生物。本发明还涉及上述化合物的药学上合适的酸加成盐。本发明进一步涉及包含如上所述的咪唑衍生物或其药学上合适的酸加成盐的组合物,并涉及制备此类化合物的方法。

著录项

  • 公开/公告号CL2007003653A1

    专利类型

  • 公开/公告日2008-07-11

    原文格式PDF

  • 申请/专利权人 F. HOFFMANN-LA ROCHE AG.;

    申请/专利号CL20070003653

  • 申请日2007-12-17

  • 分类号A61K31/4174;A61K31/4178;A61K31/5377;A61P25/00;A61P25/16;A61P25/22;A61P25/24;A61P25/28;C07D233/00;C07D233/64;C07D307/83;C07D405/12;C07D340/00;

  • 国家 CL

  • 入库时间 2022-08-21 20:08:35

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