IMPROVED SEQUENTIAL STEP DOWN THERAPY FOR TREATING RESISTANT BACTERIAL INFECTIONS CAUSED BY ESBLs PRODUCING STRAIN

摘要

The present invention provides a method for treating a resistant bacterial infections caused by ESBLs producing strain in a subject in need thereof, which comprises a) administering a pharmaceutical dosage form comprising cefepime in combination with sulbactam and pharmaceutically acceptable excipients via parenteral route, followed by b) oral third generation cephalosporin with a suitable β lactamase inhibitor after a suitable interval.