Indol derivative (SGLT) as sodium derivative glucose carrier inhibitor

摘要

It refers to indol derivative from formula (I) containing fluorine or chlorine; R2 is h or fluorine. The most popular compounds are: 4-chloro-3 - (4-cycloacrylonitrile-3) - 1 - (b-d-glucose-pyridinol) - Indian glycol, 3 - (4-cycloacrylonitrile) - 4-fluoro-1 - (b-d-glucose-pyridinol) Indian glycol, 4-chloro-3 - (4-cycloacrylonitrile-3) - 6-fluoro-1 - (b-d-glucose-pyranol) Indian glycol, etc. He also mentioned a preparatory process and a pharmacology composer. These compounds are inhibitors of sodium glucose transporter (ghlt) and are useful in the treatment of type 1 and type 2 diabetes, hyperglycemia, obesity, and allergic reactions.