AMIDES OF PYRROLOPYRIDINE-2-CARBOXYLIC ACID AS INHIBITORS OF GLYCOGEN PHOSPHORYLASE, METHOD FOR THEIR SYNTHESIS, DRUG FORMULATION, AND THEIR USE AS THERAPEUTIC AGENTS

摘要

Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyper-insulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.I