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Developing Inhibitors of Translesion DNA Synthesis as Therapeutic Agents against Lung Cancer.

机译：开发Translesion DNa合成抑制剂作为治疗肺癌的药物。

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作者
Bardis, A. J.;
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年度 2015
页码 1-27
总页数 27
原文格式 PDF
正文语种 eng
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关键词
Lung cancer; Chemotherapeutic agents; Inhibitors; Pharmacologic actions; Deoxyribonucleic acids; Nucleotides; Synthesis (chemistry); Mutations; Mutagenesis; Dna polymerases; Nucleoslde analogs; Chemosensitizers;

机译：肺癌;化学治疗剂;抑制剂;药理作用;脱氧核糖核酸;核苷酸;合成（化学）;突变;诱变; Dna聚合酶;核苷类似物;化学增敏剂;

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2. Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer. [J] . Luchenko VL, Salcido CD, Zhang Y, Cell cycle . 2011,第18期

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3. Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents [J] . Alagumuthu Manikandan, Arumugam Sivakumar Bioorganic and medicinal chemistry . 2017,第4期

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4. PCNA trimer instability inhibits translesion synthesis by DNA polymerase η and by DNA polymerase δ [J] . DieckmanL.M., WashingtonM.T. DNA repair . 2013,第5期

机译：PCNA三聚体不稳定性通过DNA聚合酶η和DNA聚合酶δ抑制跨病变的合成
5. Ruthenium Complexes as Therapeutic Agents: Investigating the Chemistry of the Dinuclear MCU-Inhibitor Ru360 - (PPT) [C] . Sarah Nathan International Precious Metals Institute Annual Conference . 2017

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6. Enhancing the Therapeutic Effects of Low Doses of Ionizing Radiation in Non-Small Cell Lung Cancers Using a Combination of PARP Inhibitors and DNA Demethylating Agents. [D] . Biondi, Christopher Anthony. 2016

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7. Inhibiting translesion DNA synthesis as an approach to combat drug resistance to DNA damaging agents [O] . Jung-Suk Choi, Seol Kim, Edward Motea, 2017

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8. Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancer. [O] . Abhay Kumar Singh, Ratnakar Singh, Farhat Naz, 2012

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9. Developing Inhibitors of Translesion DNA Synthesis as Therapeutic Agents Against Lung Cancer. [R] . Berdis, A. J. 2014

机译：开发Translesion DNa合成抑制剂作为治疗肺癌的药物。

Developing Inhibitors of Translesion DNA Synthesis as Therapeutic Agents against Lung Cancer.

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