COMBINATIONS AND COMPOSITIONS THAT INTERFER WITH THE FUNCTION OF VEGF / VEGF RECEIVER AND ANGIOPOYETINA / TIE RECEIVER, AND ITS USE (II).

摘要

Pharmaceutical compositions comprising a combination of compound I and compound II, wherein compound I and compound II comprise at least one of (i) a compound of general formula I in which r has the meaning of 0 to 2, n has the meaning of 0 to 2; R3 and R4 a) each, independently of each other, have the meaning of lower alkyl, b) together form a bridge of partial general formula II, where the union takes place via the two terminal atoms C, and m has the meaning of 0 to 4; or c) together form a bridge of partial formula III where one or two of the ring members T1, T2, T3, T4 has the meaning of nitrogen, and each of the remaining has the meaning of CH, and the union takes place via the atoms T1 and T4.