SYSTEM OF ADMINISTRATION OF A TETRAHYDROXYLED STROGEN DRUG INTENDED FOR HORMONAL CONTRACEPTION.

摘要

Use of an estrogenic component selected from the group consisting of: substances represented by the following formula (See formula) in which R1, R2, R3, R4 independently represent a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; each of R5, R6, R7 is a hydroxyl group; and no more than 3 of R1, R2, R3, R4 are hydrogen atoms; precursors capable of releasing a substance according to the aforementioned formula when used in the present method, these precursors being derived from the mentioned estrogenic substances, where the hydrogen atom of at least one of the hydroxyl groups has been replaced by an acyl radical of a carboxylic hydrocarbon, sulfonic acid or sulfamic acid of 1-25 carbon atoms; tetrahydrofuranyl; tetrahydropyranal; or a straight or branched chain glycosidic residue containing 1-20 glycosidic units per residue; and mixtures of one or more of the aforementioned substances and / or precursors; in an oral contraceptive that also contains a progestogenic component, where the oral contraceptive does not contain LHRH.