AT1-RECEPTOR ANTAGONISTS FOR PREVENTING AND TREATING POSTISCHEMIC RENAL FAILURE AND FOR PROTECTING ISCHEMIC KIDNEYS

摘要

AT1-receptor antagonistsand particularly the compound(S)-N-(1-carboxy-2-methylprop-1-yl)-N--pentanoyl-N-[2' (1H-tetrazol-5-yl)biphenyl--4-yl-methyl]amine(valsartan) of formula(I) or a salt thereof, in particular apharmaceutically acceptable salt thereof,can be used for treating (acute andchronic) postischemic renal failure and forprotecting the ischemic kidney.