COMPOSITION AND METHOD FOR ALLEVIATING IMPAIRED MENTAL FUNCTION AND MEMORY LOSS IN MAMMALS

摘要

A composition and method of alleviating impaired mental function and memory loss in mammals, the method comprising treating the mammal with a non-toxic, enhancing effective amount of a cell membrane permeant calcium buffer. The buffer is preferably a calcium ion chelating agent having a K D selected from the range 1 × 10 -4 to 1 × 10 -8 Molar and being essentially calcium ion-selective over other metal ions. A most preferred buffer is BAPTA-AM.